A team of investigators from nine institutions has shed light on how cells transmit taste information to the brain for three out of the five primary taste types, sweet, bitter, and umami. They have discovered how ATP - the body's main fuel source- is released as the neurotransmitter from sweet, bitter, and umami, or savory, taste bud cells. The CALHM1 channel protein, which spans a taste bud cell's outer membrane to allow ions and molecules in and out, ...
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