A natural defense mechanism against invading organisms and tissue injury is inflammation. In acute inflammation, the pathogen or inflammatory mediators are cleared away and homeostasis is reached, however in chronic inflammatory states, this resolving response is impaired, leading to chronic inflammation and tissue damage. It is now widely believed that an impaired resolution of inflammation is a major contributing factor to the progression of a number of devastating ...
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New research reveals that B cells regulate obesity-associated inflammation and type 2 diabetes through two specific mechanisms. The research is from Boston University School of Medicine (BUSM). The study, published in the iProceedings of the National Academies of Sciences/i, indicates the importance of continuing to explore B cells as a therapeutic target to treat these diseases. Barbara Nikolajczyk, PhD, associate professor of microbiology at BUSM, is the study's senior ...
