Johns Hopkins researchers stumbled upon mutations associated with familial partial lipodystrophy (FPLD), a rare disease that disrupts normal patterns of fat distribution throughout the body while studying a protein that gives structure to the nucleus of cells. "Our findings open new paths for learning how and why fat cells are disproportionately affected by mutations in the protein lamin A, which is found in the nucleus of most cells of the body," says Katherine ...
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A peptide, or protein, derived from Pacific cod that may inhibit prostate cancer and other cancers from spreading has been identified by researchers at the University of Maryland School of Medicine. The preclinical research is published online in the iProceedings of the National Academy of Sciences/i (PNAS). "The use of natural dietary products with anti-tumor activity is an important and emerging field of research," says senior author Hafiz Ahmed, Ph.D., assistant ...
Researchers have found that macrophages - white blood cells that play a key role in the immune response - also help to both produce and eliminate the body's red blood cells (RBCs). The researchers are from the Albert Einstein College of Medicine of Yeshiva University and the Icahn School of Medicine at Mount Sinai. It is hoped that the findings could lead to novel therapies for diseases or conditions in which the red blood cell production is thrown out of balance. ...
Researchers are currently developing a new vaccine to treat cytomegalovirus (CMV) infection, which is the leading infectious cause of congenital birth defects, affecting one in every 750 children born who develop permanent disabilities such as brain damage or hearing loss. Researchers from the La Jolla Institute for Allergy (and) Immunology and Cardiff University in Wales (UK) have discovered a previously unknown cellular mechanism that could prove critical in creating ...
A unique monoclonal antibody that can help anticancer agents to effectively reach inside a cancer cell and target proteins vital for the survival of the cell has been discovered by American researchers. Scientists from Memorial Sloan-Kettering Cancer Center and Eureka Therapeutics have collaborated to create the new human monoclonal antibody, which targets a protein associated with many types of cancer and is of great interest to cancer researchers. Unlike ...
